We Treat Infertility Since 1989 using Clean Laboratory Protocol (CLP)
since 1989

Main Hospital

V. V. Road, Pattoor,
Thiruvananthapuram, 695035. Kerala, S.India.
Phone: +91-471-2451926 / 2474203

Treatment options

Treatment options ( ART / IVF Treatment)
ART / IVF Treatment will depend on the cause of the infertility and the acceptability of the method by the couple. Discussion and counseling before implementation of decision.

  • Intra Uterine Insemination (IUI)
    Injection of sperm into the uterinre cavity. Done under ultra sound guidance for the correct deposition of sperm to the fundal region, using the processed semen from husband / donor. Beneficial for women with unexplained infertility, poor / hostile cervical mucus & men with oligoastheno zoospermia. IUI is done in natural and stimulated cycles.
  • Intra Cervical Insemination (ICI)
    Injection of sperm into cervical canal of the uterus. Intra Cervical Insemination (ICI) is performed with donor semen in normal wives of Azoospermic husbands.

In Vitro Fertilisation (IVF)
Union and fertlisation of sperm and egg in the laboratory outside the female pelvis; instaed of inside the female pelvis in normal pregnancy.

InVitro Fertilisation (IVF) & Embryo Transfer (ET)
Involves controlled ovarian stimulation (COH), ultrasound guided ovum aspiration, insemination of ovum, incubation of gametes in CO2 incubator and transfer of embryos (ET) into uterus under ultrasound.

  • First stage : Education
    At this stage, information is provided regarding the procedures, treatment plan and how the treatment plan is going to work. Required consent forms are signed.
  • Second stage : The suppression of the pituitary
    Full suppression of the female ovaries using GnRH Agonists or GnRH antagonists. These medications applied either as nasal sprays or subcutaneous injections will prevent you from ovulating before the right time. Type and duration of suppression will depend on the previous medical history and present clinical status. The proceesure starts from the 22 day of the previous cycle to 36 hours before OPU.
  • Third stage: The stimulation of the ovaries and the monitoring of egg development
    The sucess of in vitro fertilisation treatment depends on the production of a multitude of eggs in the female ovaries. For this purpose, the ovaries which have been suppressed with the above-mentioned medications get stimulated with medications which stimulate egg development. These medications are injected subcutaneously or intramuscularly.

    It takes approximately 10 Days for your ovaries to be stimulated through these medications. You have to be checked out a couple of times throughout this process for the monitoring of your egg development. During those checks ultrasonography will be performed and if deemed necessary the hormone levels in your blood will be checked to readjust the dosage of your medications. The duration is 10 -15 days from the day 2 (D2) of the period and ends with egg collection.
  • Fourth stage: Egg collection
    During the monitoring of egg development, on the day it is determined that a sufficient number of eggs have matured, HCG (Human Chronic Gonadotropin) injection is carried out in order for the eggs to complete their final step of maturation, the collection of the eggs is scheduled for the 34-35 hours following this final medication injection.

    You may be given a sedative or a medication to make you drowsy during egg collection. Alternatively the entire procedure may be performed under full anesthesia. The procedure is similar to the vaginal ultrasonography performed during your egg development follow ups. The only difference is the needle connected to the vaginal ultrasonography device which is inserted through the vagina to collect the eggs inside your ovaries.

    The procedure lasts for an average of 30 minutes, then the Oocytes are inseminated with processed sperm from husband and donor. Fertilisation with sperm cells takes on the same day that the eggs are collected.
  • Fifth Stage: Laboratory procedures
    One day after the egg collection the couple is informed about the number of eggs fertilised normally following this stage the normally fertilised eggs are monitored under laboratory conditions for 2 to 5 days. When the time is right the most superior quality ones among them are carefully selected in certain numbers and placed back in the mother’s uterus. The couple gets informed on the timing of this Embryo transfer / blastocyst transfer procedure.
  • Sixth stage: Embryo transfer
    Prior to transfer procedure the couple is informed on the number and the quality of the embryos to be transfered.Transfer procedure is no different than a simple examination procedure. Anesthesia is optional.

    The only requirement before the procedure is for the mother to drink a lot of water inorder to fill up the bladder. The tranfer procedure is performed under ultrasonographic observation which requires the bladder to be partially full.

    During transfer procedure a catheter loaded with embryos is passed through the vagina and the cervix and placed inside the uterus.and the embryos are released inside the uterus. If there remains any superior quality embryos following the transfer consent is obtained from the couple to freeze and keep those embryo for future use.

    Following the transfer the couple is kept in the hospital for rest for 3-4 hours and later sent home. The woman is advised to spend the day resting inorder to support the pregnancy. she will be started on hormones, once the eggs have been collected and the embryos have been transfered. The result of the treatment may be found out with the help of a pregnancy test 14 days after the transfer . If the result is positive an ultrasonography appointment is made to observe the heart rate of the baby within 3weeks.

Intra Cytoplasmic Sperm Injection (ICSI) - Ejaculated sperm
ICSI is the injection of single sperm in to the ovum, thereby increasing the chances of fertilization and development of embryos. ICSI is done in conjunction with IVF- ET. ICSI is indicated in

  • Fertilization failure in IVF
  • Male infertility
  • Structural defects of Testis
  • Unsuccessful reversal vasectomy

Intra Cytoplasmic Sperm Injection (ICSI) - Extracted sperm
Testicular sperm extraction (TESE) / precutaneous epididymal sperm aspiration (PESA) /Micro Epididymal Sperm Aspiration (MESA) is performed by Urologist / Andrologist for the purpose of extracting sperm for ICSI in severe anatomical defects in the male.


Donor programme - Third party reproduction (semen, ovum & embryo)
Semen, ovum and embryo donors are selected after adequate screening. For men with severe defects (Azoospermia & Aspermia). For women with ovarian failure in natural & stimulated cycles.

  • Repeated poor quality ovum in IVF cycles
  • Repeated fertilisation failure
  • Upper age group (>40 years)

For third party reproduction, we arrange the samples from Accredited Tissue Banks in Europe and USA, transported through sophisticated scientific logistics arrangements, using cryo can (dry shipper).


Blastocyst culture
Embryos are grown up to the stage of blasto cysts (5-6 days) before transfer to the uterus, which improves the implantation rate.


Surrogacy (Substitute Motherhood)

  • For women with severe uterine abnormality
  • Loss of children after hysterectomy

Informed consent mandatory and appropriate counseling arranged. Surrogate women will be sourced from India or accredited agencies in Europe or USA.


Post menopausal maternity
SAMAD IVF has a good track record in the area of post manopausal maternity. Two cases, 57 years old and 62 years old post menopausal ladies delivered live healthy babies in our hospital which created headlines in the media.


Genetic study
Preimplantation genetic study (PGS) and preimplantation genetic diagnosis (PGD) will be arranged for indicated couples.


High risk pregnancy
All ART /IVF pregnancy is considered high risk pregnancy, and all test tube babies are categorised as precious babies and taken care of accordingly. Overseas patients can return home after embryo transfer, and if they wish, they can come back for pregnancy monitoring with 3D/4D ultra sound scanner and deliver the baby at SAMAD IVF.


Facility at SAMD IVF
Assisted Reproductive Technology unit (ART - Test tube Baby procedure)
Attached with HEPA filtered pressure module laminar flow air system laboratory and operation theatre (IVF, Lab & IVF OT). Our state of the art ART laboratory has all the modern facilities / equipments like Inverted Microscope with micro manipulator, sterio microscope, carbon dioxide incubators, laminar flow work benches, aspiration pump, embryo freezer unit etc.